MHCI Weekly Benchmark results
Overall scores
Overall scores based on data sets submitted to the IED for the last at least 5 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.
Server | Overall | SRCC | AUC |
---|---|---|---|
ANN 3.4 | 64 | 68 | 60 |
ANN 4.0 | 56 | 56 | 55 |
ARB | 28 | 22 | 34 |
IEDB Consensus | 37 | 33 | 42 |
NetMHCcons | 67 | 68 | 66 |
NetMHCpan 2.8 | 50 | 50 | 51 |
NetMHCpan 3.0 | 56 | 58 | 54 |
NetMHCpan 4.0 BA | - | - | - |
NetMHCpan 4.0 EL | - | - | - |
NetMHCpan 4.1 BA | - | - | - |
NetMHCpan 4.1 EL | - | - | - |
PickPocket | 27 | 14 | 39 |
SMM | 44 | 43 | 45 |
SMMPMBEC | 37 | 41 | 33 |
mhcflurry 1.2.0 | 93 | 96 | 91 |
Data set specific results
Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here
Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.
IEDB Reference |
Allele | Peptide Length |
Peptide Count |
Positive Count |
Measurement type |
ANN 3.4 | ANN 4.0 | ARB | IEDB Consensus | NetMHCcons | NetMHCpan 2.8 | NetMHCpan 3.0 | NetMHCpan 4.0 BA | NetMHCpan 4.0 EL | NetMHCpan 4.1 BA | NetMHCpan 4.1 EL | PickPocket | SMM | SMMPMBEC | mhcflurry 1.2.0 | |||||||||||||||
SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | ||||||
1024516 | HLA-A*02:01 | 9 | 51 | 45 | ic50 | 0.673 | 0.639 | 0.674 | 0.633 | 0.658 | 0.648 | 0.615 | 0.572 | 0.672 | 0.633 | 0.666 | 0.633 | 0.649 | 0.626 | - | - | - | - | - | - | - | - | 0.591 | 0.659 | 0.691 | 0.641 | 0.677 | 0.630 | 0.753 | 0.711 |
1024516 | HLA-A*02:01 | 10 | 32 | 28 | ic50 | 0.545 | 0.688 | 0.529 | 0.643 | 0.532 | 0.643 | 0.543 | 0.674 | 0.555 | 0.692 | 0.537 | 0.696 | 0.530 | 0.616 | - | - | - | - | - | - | - | - | 0.439 | 0.661 | 0.537 | 0.670 | 0.523 | 0.621 | 0.753 | 0.848 |
1024516 | HLA-A*02:02 | 9 | 51 | 44 | ic50 | 0.653 | 0.739 | 0.601 | 0.718 | 0.511 | 0.756 | 0.563 | 0.680 | 0.632 | 0.747 | 0.599 | 0.721 | 0.601 | 0.776 | - | - | - | - | - | - | - | - | 0.504 | 0.700 | 0.552 | 0.687 | 0.566 | 0.727 | 0.862 | 0.925 |
1024516 | HLA-A*02:03 | 9 | 51 | 42 | ic50 | 0.539 | 0.684 | 0.534 | 0.675 | 0.536 | 0.728 | 0.422 | 0.665 | 0.562 | 0.709 | 0.565 | 0.720 | 0.564 | 0.746 | - | - | - | - | - | - | - | - | 0.475 | 0.772 | 0.528 | 0.683 | 0.541 | 0.693 | 0.625 | 0.717 |
1024516 | HLA-A*02:03 | 10 | 32 | 25 | ic50 | 0.378 | 0.794 | 0.399 | 0.777 | 0.361 | 0.731 | 0.304 | 0.720 | 0.376 | 0.806 | 0.308 | 0.760 | 0.360 | 0.771 | - | - | - | - | - | - | - | - | 0.162 | 0.714 | 0.310 | 0.720 | 0.303 | 0.703 | 0.725 | 0.920 |
1024516 | HLA-A*02:06 | 9 | 51 | 34 | ic50 | 0.709 | 0.813 | 0.712 | 0.824 | 0.663 | 0.777 | 0.681 | 0.785 | 0.733 | 0.830 | 0.718 | 0.825 | 0.718 | 0.829 | - | - | - | - | - | - | - | - | 0.545 | 0.760 | 0.682 | 0.787 | 0.679 | 0.787 | 0.874 | 0.924 |
1024516 | HLA-A*02:06 | 10 | 32 | 10 | ic50 | 0.568 | 0.823 | 0.501 | 0.877 | 0.534 | 0.850 | 0.574 | 0.850 | 0.596 | 0.836 | 0.605 | 0.850 | 0.583 | 0.882 | - | - | - | - | - | - | - | - | 0.463 | 0.764 | 0.576 | 0.841 | 0.592 | 0.850 | 0.822 | 0.909 |
1024516 | HLA-A*68:02 | 9 | 51 | 15 | ic50 | 0.586 | 0.857 | 0.595 | 0.863 | 0.473 | 0.800 | 0.559 | 0.838 | 0.576 | 0.852 | 0.566 | 0.839 | 0.584 | 0.850 | - | - | - | - | - | - | - | - | 0.537 | 0.863 | 0.562 | 0.831 | 0.552 | 0.826 | 0.604 | 0.856 |
1024516 | HLA-A*68:02 | 10 | 32 | 6 | ic50 | 0.467 | 0.814 | 0.515 | 0.776 | 0.374 | 0.782 | 0.424 | 0.827 | 0.355 | 0.763 | 0.275 | 0.705 | 0.414 | 0.763 | - | - | - | - | - | - | - | - | 0.310 | 0.776 | 0.413 | 0.821 | 0.361 | 0.808 | 0.482 | 0.821 |
1028553 | HLA-A*02:01 | 9 | 22 | 2 | ic50 | 0.700 | 0.950 | 0.632 | 0.925 | 0.686 | 0.900 | 0.579 | 0.850 | 0.641 | 0.925 | 0.617 | 0.925 | 0.590 | 0.850 | - | - | - | - | - | - | - | - | 0.577 | 0.825 | 0.591 | 0.850 | 0.624 | 0.825 | 0.763 | 0.975 |
1028553 | HLA-B*07:02 | 9 | 22 | 3 | ic50 | 0.758 | 0.921 | 0.645 | 0.895 | 0.553 | 0.877 | 0.675 | 0.877 | 0.717 | 0.912 | 0.662 | 0.895 | 0.670 | 0.895 | - | - | - | - | - | - | - | - | 0.615 | 0.895 | 0.622 | 0.895 | 0.623 | 0.877 | 0.683 | 0.912 |
1028554 | HLA-A*02:01 | 9 | 44 | 7 | ic50 | 0.620 | 0.828 | 0.598 | 0.811 | 0.507 | 0.761 | 0.505 | 0.855 | 0.688 | 0.888 | 0.696 | 0.888 | 0.708 | 0.876 | - | - | - | - | - | - | - | - | 0.506 | 0.880 | 0.581 | 0.898 | 0.547 | 0.861 | 0.631 | 0.907 |
1028554 | HLA-B*07:02 | 9 | 52 | 6 | ic50 | 0.698 | 0.884 | 0.670 | 0.833 | 0.654 | 0.757 | 0.594 | 0.862 | 0.729 | 0.862 | 0.617 | 0.772 | 0.627 | 0.790 | - | - | - | - | - | - | - | - | 0.704 | 0.743 | 0.661 | 0.851 | 0.704 | 0.855 | 0.862 | 0.924 |
1028554 | HLA-B*35:01 | 9 | 56 | 3 | ic50 | 0.273 | 0.566 | 0.266 | 0.686 | 0.260 | 0.642 | 0.288 | 0.761 | 0.355 | 0.642 | 0.364 | 0.679 | 0.401 | 0.673 | - | - | - | - | - | - | - | - | 0.284 | 0.503 | 0.206 | 0.591 | 0.204 | 0.528 | 0.503 | 0.811 |
1028554 | HLA-B*44:03 | 9 | 46 | 3 | ic50 | 0.559 | 0.651 | 0.651 | 0.736 | 0.249 | 0.558 | 0.557 | 0.907 | 0.546 | 0.643 | 0.457 | 0.612 | 0.598 | 0.636 | - | - | - | - | - | - | - | - | 0.427 | 0.643 | 0.466 | 0.752 | 0.549 | 0.760 | 0.773 | 0.690 |
1028554 | HLA-B*57:01 | 9 | 53 | 10 | ic50 | 0.519 | 0.944 | 0.526 | 0.958 | 0.124 | 0.628 | 0.334 | 0.798 | 0.563 | 0.916 | 0.619 | 0.863 | 0.638 | 0.865 | - | - | - | - | - | - | - | - | 0.445 | 0.849 | 0.331 | 0.765 | 0.290 | 0.772 | 0.624 | 0.970 |
315174 | HLA-B*27:03 | 9 | 11 | 7 | binary | - | - | - | - | - | - | - | - | 0.657 | 0.893 | 0.657 | 0.893 | 0.538 | 0.821 | - | - | - | - | - | - | - | - | 0.657 | 0.893 | - | - | - | 0.500 | 0.777 | 0.964 |
1028790 | HLA-A*02:01 | 9 | 55 | 47 | ic50 | 0.610 | 0.565 | 0.611 | 0.564 | 0.580 | 0.566 | 0.556 | 0.513 | 0.613 | 0.566 | 0.615 | 0.574 | 0.607 | 0.577 | - | - | - | - | - | - | - | - | 0.586 | 0.660 | 0.625 | 0.564 | 0.610 | 0.553 | - | - |
1028790 | HLA-A*02:01 | 10 | 35 | 31 | ic50 | 0.453 | 0.669 | 0.441 | 0.637 | 0.439 | 0.637 | 0.456 | 0.657 | 0.443 | 0.677 | 0.407 | 0.677 | 0.433 | 0.605 | - | - | - | - | - | - | - | - | 0.303 | 0.645 | 0.468 | 0.653 | 0.449 | 0.593 | 0.670 | 0.839 |
1028790 | HLA-A*02:02 | 9 | 55 | 45 | ic50 | 0.639 | 0.744 | 0.587 | 0.724 | 0.494 | 0.733 | 0.564 | 0.712 | 0.620 | 0.747 | 0.582 | 0.713 | 0.589 | 0.753 | - | - | - | - | - | - | - | - | 0.531 | 0.721 | 0.557 | 0.714 | 0.572 | 0.742 | 0.859 | 0.911 |
1028790 | HLA-A*02:03 | 9 | 55 | 43 | ic50 | 0.509 | 0.668 | 0.495 | 0.655 | 0.501 | 0.684 | 0.417 | 0.657 | 0.537 | 0.694 | 0.539 | 0.696 | 0.535 | 0.714 | - | - | - | - | - | - | - | - | 0.503 | 0.766 | 0.519 | 0.678 | 0.530 | 0.686 | 0.583 | 0.694 |
1028790 | HLA-A*02:03 | 10 | 35 | 28 | ic50 | 0.314 | 0.781 | 0.292 | 0.760 | 0.289 | 0.684 | 0.276 | 0.709 | 0.291 | 0.791 | 0.208 | 0.750 | 0.269 | 0.755 | - | - | - | - | - | - | - | - | 0.070 | 0.704 | 0.335 | 0.730 | 0.313 | 0.699 | 0.687 | 0.923 |
1028790 | HLA-A*02:06 | 9 | 55 | 36 | ic50 | 0.620 | 0.757 | 0.622 | 0.765 | 0.566 | 0.725 | 0.585 | 0.730 | 0.642 | 0.773 | 0.630 | 0.770 | 0.631 | 0.778 | - | - | - | - | - | - | - | - | 0.528 | 0.750 | 0.588 | 0.732 | 0.587 | 0.732 | 0.820 | 0.876 |
1028790 | HLA-A*02:06 | 10 | 35 | 12 | ic50 | 0.552 | 0.754 | 0.512 | 0.819 | 0.495 | 0.775 | 0.545 | 0.779 | 0.574 | 0.761 | 0.572 | 0.768 | 0.575 | 0.822 | - | - | - | - | - | - | - | - | 0.387 | 0.656 | 0.560 | 0.790 | 0.588 | 0.801 | 0.820 | 0.884 |
1028790 | HLA-A*68:02 | 9 | 55 | 16 | ic50 | 0.557 | 0.835 | 0.552 | 0.829 | 0.448 | 0.761 | 0.529 | 0.814 | 0.548 | 0.825 | 0.534 | 0.806 | 0.544 | 0.814 | - | - | - | - | - | - | - | - | 0.448 | 0.798 | 0.536 | 0.811 | 0.524 | 0.801 | 0.575 | 0.825 |
1028790 | HLA-A*68:02 | 10 | 35 | 8 | ic50 | 0.432 | 0.699 | 0.460 | 0.648 | 0.314 | 0.729 | 0.372 | 0.699 | 0.330 | 0.667 | 0.272 | 0.620 | 0.357 | 0.616 | - | - | - | - | - | - | - | - | 0.295 | 0.662 | 0.383 | 0.718 | 0.337 | 0.685 | 0.410 | 0.671 |