Automated Server Benchmarks

MHCI Weekly Benchmark results

Overall scores

Overall scores based on data sets submitted to the IED for the last at least 1 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server	Overall	SRCC	AUC
ANN 3.4	68	64	71
ANN 4.0	61	57	64
ARB	11	14	7
IEDB Consensus	29	29	29
NetMHCcons	75	71	79
NetMHCpan 2.8	54	50	57
NetMHCpan 3.0	82	79	86
NetMHCpan 4.0 BA	89	86	93
NetMHCpan 4.0 EL	11	7	14
NetMHCpan 4.1 BA	-	-	-
NetMHCpan 4.1 EL	-	-	-
PickPocket	21	21	21
SMM	36	36	36
SMMPMBEC	43	43	43
mhcflurry 1.2.0	71	93	50

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.

IEDB Reference	Allele	Peptide Length	Peptide Count	Positive Count	Measurement type	ANN 3.4		ANN 4.0		ARB		IEDB Consensus		NetMHCcons		NetMHCpan 2.8		NetMHCpan 3.0		NetMHCpan 4.0 BA		NetMHCpan 4.0 EL		NetMHCpan 4.1 BA		NetMHCpan 4.1 EL		PickPocket		SMM		SMMPMBEC		mhcflurry 1.2.0
IEDB Reference	Allele	Peptide Length	Peptide Count	Positive Count	Measurement type	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC
1031894	HLA-A*02:01	9	434	368	ic50	0.720	0.882	0.717	0.880	0.546	0.767	0.633	0.817	0.729	0.885	0.716	0.878	0.739	0.899	0.742	0.901	0.529	0.779	-	-	-	-	0.567	0.788	0.645	0.819	0.648	0.825	0.745	0.864