IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IED for the last at least 5 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
ANN 3.4 62 61 63
ANN 4.0 66 60 73
ARB 41 31 51
IEDB Consensus 71 66 77
NetMHCcons 58 56 60
NetMHCpan 2.8 58 56 60
NetMHCpan 3.0 56 59 54
NetMHCpan 4.0 BA 71 74 67
NetMHCpan 4.0 EL 36 34 39
NetMHCpan 4.1 BA 75 76 74
NetMHCpan 4.1 EL 51 49 54
PickPocket 53 47 59
SMM 74 69 80
SMMPMBEC 78 73 83
mhcflurry 1.2.0 49 40 57

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


IEDB
Reference		 Allele Peptide
Length		 Peptide
Count		 Positive
Count		 Measurement
type		 ANN 3.4 ANN 4.0 ARB IEDB Consensus NetMHCcons NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 BA NetMHCpan 4.0 EL NetMHCpan 4.1 BA NetMHCpan 4.1 EL PickPocket SMM SMMPMBEC mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1035424   H-2-Kb   9   13   8   binary   0.423   0.750   0.338   0.700   0.254   0.650   0.571   0.838   0.338   0.700   0.296   0.675   0.127   0.575   0.254   0.650   0.085   0.550   0.296   0.675   0.211   0.625   0.127   0.575   0.507   0.800   0.592   0.850   -0.085   0.450 
 1037140   HLA-A*02:01   9   12   3   ic50   0.557   0.815   0.592   0.889   0.588   0.926   0.582   0.889   0.616   0.852   0.595   0.852   0.634   0.852   0.683   0.889   0.123   0.741   0.644   0.889   0.543   0.778   0.599   0.889   0.630   0.926   0.630   0.926   0.585   0.889 
 1037261   HLA-B*07:02   9   52   50   binary   0.200   0.800   0.233   0.850   0.033   0.550   0.258   0.885   0.187   0.780   0.200   0.800   0.187   0.780   0.193   0.790   0.157   0.735   0.200   0.800   0.187   0.780   0.167   0.750   0.267   0.900   0.267   0.900   0.253   0.880 
 1037198   HLA-A*02:01   9   18   16   binary   0.546   1.000   0.545   1.000   0.545   1.000   0.547   1.000   0.545   1.000   0.545   1.000   0.545   1.000   0.545   1.000   0.545   1.000   0.545   1.000   0.545   1.000   0.545   1.000   0.545   1.000   0.545   1.000   0.545   1.000 
 1037014   HLA-A*02:01   9   16   11   binary   0.629   0.891   0.600   0.873   0.541   0.836   0.573   0.855   0.629   0.891   0.600   0.873   0.659   0.909   0.687   0.927   0.658   0.909   0.687   0.927   0.687   0.927   0.658   0.909   0.541   0.836   0.542   0.836   0.570   0.855