MHCI Weekly Benchmark results
Overall scores
Overall scores based on data sets submitted to the IED for the last at least 16 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.
Server | Overall | SRCC | AUC |
---|---|---|---|
ANN 3.4 | 66 | 66 | 67 |
ANN 4.0 | 56 | 52 | 60 |
ARB | 50 | 45 | 56 |
IEDB Consensus | 52 | 51 | 52 |
NetMHCcons | 67 | 65 | 69 |
NetMHCpan 2.8 | 61 | 60 | 62 |
NetMHCpan 3.0 | 65 | 65 | 65 |
NetMHCpan 4.0 BA | 70 | 71 | 69 |
NetMHCpan 4.0 EL | 39 | 38 | 39 |
NetMHCpan 4.1 BA | 78 | 76 | 80 |
NetMHCpan 4.1 EL | 45 | 42 | 48 |
PickPocket | 48 | 46 | 50 |
SMM | 50 | 48 | 51 |
SMMPMBEC | 56 | 52 | 59 |
mhcflurry 1.2.0 | 60 | 55 | 64 |
Data set specific results
Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here
Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.
IEDB Reference |
Allele | Peptide Length |
Peptide Count |
Positive Count |
Measurement type |
ANN 3.4 | ANN 4.0 | ARB | IEDB Consensus | NetMHCcons | NetMHCpan 2.8 | NetMHCpan 3.0 | NetMHCpan 4.0 BA | NetMHCpan 4.0 EL | NetMHCpan 4.1 BA | NetMHCpan 4.1 EL | PickPocket | SMM | SMMPMBEC | mhcflurry 1.2.0 | |||||||||||||||
SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | ||||||
1034799 | H-2-Db | 9 | 46 | 42 | ic50 | 0.736 | 0.988 | 0.714 | 0.964 | 0.565 | 0.952 | 0.643 | 0.935 | 0.731 | 0.958 | 0.675 | 0.940 | 0.728 | 0.952 | 0.717 | 0.946 | 0.631 | 0.905 | - | - | - | - | 0.496 | 0.810 | 0.616 | 0.893 | 0.648 | 0.917 | 0.787 | 0.964 |
1034799 | H-2-Kb | 8 | 34 | 31 | ic50 | 0.679 | 0.903 | 0.651 | 0.925 | 0.580 | 0.839 | 0.662 | 0.914 | 0.671 | 0.914 | 0.665 | 0.914 | 0.635 | 0.903 | 0.642 | 0.882 | 0.556 | 0.828 | - | - | - | - | 0.513 | 0.806 | 0.639 | 0.903 | 0.623 | 0.871 | 0.644 | 0.925 |
315301 | HLA-B*39:09 | 9 | 10 | 3 | binary | - | - | - | - | - | - | - | - | 0.798 | 1.000 | 0.798 | 1.000 | 0.798 | 1.000 | 0.798 | 1.000 | 0.798 | 1.000 | - | - | - | - | 0.798 | 1.000 | - | - | - | - | - | - |
1034596 | HLA-A*02:01 | 9 | 10 | 8 | binary | 0.087 | 0.562 | 0.087 | 0.562 | 0.261 | 0.688 | 0.088 | 0.562 | 0.087 | 0.562 | 0.000 | 0.500 | 0.087 | 0.562 | 0.087 | 0.562 | 0.000 | 0.500 | - | - | - | - | 0.087 | 0.562 | 0.087 | 0.562 | 0.087 | 0.562 | 0.087 | 0.562 |
1035634 | HLA-C*12:02 | 9 | 16 | 13 | binary | - | - | - | - | - | - | - | - | 0.643 | 0.974 | 0.643 | 0.974 | 0.677 | 1.000 | 0.643 | 0.974 | 0.677 | 1.000 | - | - | - | - | 0.469 | 0.846 | - | - | - | - | - | - |
315217 | HLA-B*27:01 | 9 | 16 | 12 | binary | - | - | - | - | - | - | - | - | 0.658 | 0.938 | 0.658 | 0.938 | 0.532 | 0.854 | 0.470 | 0.812 | 0.501 | 0.833 | - | - | - | - | 0.454 | 0.802 | - | - | - | - | - | - |
315217 | HLA-B*27:02 | 9 | 19 | 16 | binary | - | - | - | - | - | - | - | - | 0.527 | 0.917 | 0.527 | 0.917 | 0.632 | 1.000 | 0.632 | 1.000 | 0.553 | 0.938 | - | - | - | - | 0.422 | 0.833 | - | - | - | - | 0.606 | 0.979 |
1035477 | HLA-A*30:01 | 9 | 18 | 3 | binary | 0.474 | 0.867 | 0.445 | 0.844 | 0.532 | 0.911 | 0.388 | 0.800 | 0.474 | 0.867 | 0.532 | 0.911 | 0.445 | 0.844 | 0.474 | 0.867 | 0.560 | 0.933 | - | - | - | - | 0.618 | 0.978 | 0.417 | 0.822 | - | - | 0.560 | 0.933 |
1035477 | HLA-A*30:03 | 9 | 18 | 13 | binary | - | - | - | - | - | - | - | - | 0.490 | 0.815 | 0.490 | 0.815 | 0.514 | 0.831 | 0.490 | 0.815 | 0.251 | 0.662 | - | - | - | - | 0.682 | 0.938 | - | - | - | - | - | - |
1035929 | HLA-A*02:01 | 9 | 12 | 8 | ic50 | -0.229 | 0.406 | -0.217 | 0.438 | 0.098 | 0.531 | 0.176 | 0.516 | -0.175 | 0.469 | -0.147 | 0.469 | -0.189 | 0.406 | -0.238 | 0.375 | -0.385 | 0.188 | -0.259 | 0.438 | -0.559 | 0.125 | -0.270 | 0.359 | 0.105 | 0.531 | 0.084 | 0.500 | -0.182 | 0.469 |
1036593 | HLA-A*02:01 | 9 | 14 | 9 | binary | 0.425 | 0.756 | 0.388 | 0.733 | 0.499 | 0.800 | 0.463 | 0.778 | 0.499 | 0.800 | 0.573 | 0.844 | 0.462 | 0.778 | 0.499 | 0.800 | 0.425 | 0.756 | 0.499 | 0.800 | 0.499 | 0.800 | 0.592 | 0.856 | 0.426 | 0.756 | 0.425 | 0.756 | 0.203 | 0.622 |
1036593 | HLA-A*03:01 | 10 | 11 | 7 | binary | 0.478 | 0.786 | 0.359 | 0.714 | 0.717 | 0.929 | 0.418 | 0.750 | 0.657 | 0.893 | 0.478 | 0.786 | 0.478 | 0.786 | 0.598 | 0.857 | 0.359 | 0.714 | 0.598 | 0.857 | 0.538 | 0.821 | 0.717 | 0.929 | 0.478 | 0.786 | 0.418 | 0.750 | 0.418 | 0.750 |
1036593 | HLA-A*11:01 | 10 | 11 | 6 | binary | 0.693 | 0.900 | 0.635 | 0.867 | 0.693 | 0.900 | 0.635 | 0.867 | 0.751 | 0.933 | 0.751 | 0.933 | 0.751 | 0.933 | 0.751 | 0.933 | 0.462 | 0.767 | 0.751 | 0.933 | 0.577 | 0.833 | 0.577 | 0.833 | 0.608 | 0.867 | 0.635 | 0.867 | 0.693 | 0.900 |
1036593 | HLA-B*07:02 | 9 | 19 | 9 | binary | 0.616 | 0.856 | 0.577 | 0.833 | 0.539 | 0.811 | 0.540 | 0.811 | 0.558 | 0.822 | 0.558 | 0.822 | 0.481 | 0.778 | 0.558 | 0.822 | 0.327 | 0.689 | 0.616 | 0.856 | 0.423 | 0.744 | 0.616 | 0.856 | 0.577 | 0.833 | 0.597 | 0.844 | 0.712 | 0.911 |
1036593 | HLA-B*08:01 | 9 | 12 | 8 | binary | 0.666 | 0.906 | 0.563 | 0.844 | 0.256 | 0.656 | 0.513 | 0.812 | 0.717 | 0.938 | 0.615 | 0.875 | 0.768 | 0.969 | 0.768 | 0.969 | 0.666 | 0.906 | 0.768 | 0.969 | 0.717 | 0.938 | 0.256 | 0.656 | 0.410 | 0.750 | 0.512 | 0.812 | 0.666 | 0.906 |
1035424 | H-2-Kb | 9 | 13 | 8 | binary | 0.423 | 0.750 | 0.338 | 0.700 | 0.254 | 0.650 | 0.571 | 0.838 | 0.338 | 0.700 | 0.296 | 0.675 | 0.127 | 0.575 | 0.254 | 0.650 | 0.085 | 0.550 | 0.296 | 0.675 | 0.211 | 0.625 | 0.127 | 0.575 | 0.507 | 0.800 | 0.592 | 0.850 | -0.085 | 0.450 |
1037140 | HLA-A*02:01 | 9 | 12 | 3 | ic50 | 0.557 | 0.815 | 0.592 | 0.889 | 0.588 | 0.926 | 0.582 | 0.889 | 0.616 | 0.852 | 0.595 | 0.852 | 0.634 | 0.852 | 0.683 | 0.889 | 0.123 | 0.741 | 0.644 | 0.889 | 0.543 | 0.778 | 0.599 | 0.889 | 0.630 | 0.926 | 0.630 | 0.926 | 0.585 | 0.889 |
1037261 | HLA-B*07:02 | 9 | 52 | 50 | binary | 0.200 | 0.800 | 0.233 | 0.850 | 0.033 | 0.550 | 0.258 | 0.885 | 0.187 | 0.780 | 0.200 | 0.800 | 0.187 | 0.780 | 0.193 | 0.790 | 0.157 | 0.735 | 0.200 | 0.800 | 0.187 | 0.780 | 0.167 | 0.750 | 0.267 | 0.900 | 0.267 | 0.900 | 0.253 | 0.880 |
1037198 | HLA-A*02:01 | 9 | 18 | 16 | binary | 0.546 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 | 0.547 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 | 0.545 | 1.000 |
1037014 | HLA-A*02:01 | 9 | 16 | 11 | binary | 0.629 | 0.891 | 0.600 | 0.873 | 0.541 | 0.836 | 0.573 | 0.855 | 0.629 | 0.891 | 0.600 | 0.873 | 0.659 | 0.909 | 0.687 | 0.927 | 0.658 | 0.909 | 0.687 | 0.927 | 0.687 | 0.927 | 0.658 | 0.909 | 0.541 | 0.836 | 0.542 | 0.836 | 0.570 | 0.855 |
1037619 | HLA-B*07:02 | 10 | 11 | 8 | t1/2 | 0.406 | 0.583 | 0.510 | 0.583 | 0.569 | 0.875 | 0.522 | 0.562 | 0.337 | 0.583 | 0.173 | 0.500 | 0.437 | 0.583 | 0.460 | 0.625 | 0.487 | 0.583 | 0.360 | 0.583 | 0.378 | 0.583 | 0.169 | 0.500 | 0.424 | 0.542 | 0.483 | 0.583 | 0.410 | 0.583 |
1037619 | HLA-B*07:02 | 11 | 12 | 8 | t1/2 | 0.060 | 0.562 | 0.249 | 0.656 | - | - | 0.132 | 0.562 | 0.102 | 0.562 | 0.126 | 0.562 | 0.263 | 0.625 | 0.256 | 0.688 | -0.088 | 0.469 | 0.095 | 0.594 | -0.319 | 0.375 | 0.053 | 0.500 | 0.147 | 0.562 | 0.091 | 0.375 | 0.039 | 0.562 |
1037762 | HLA-E*01:01 | 9 | 69 | 43 | binary | 0.059 | 0.535 | 0.059 | 0.535 | - | - | 0.038 | 0.523 | - | - | 0.146 | 0.587 | 0.089 | 0.553 | 0.071 | 0.542 | -0.008 | 0.495 | 0.165 | 0.598 | 0.032 | 0.519 | -0.052 | 0.471 | 0.013 | 0.509 | -0.081 | 0.452 | - | - |
1037480 | HLA-E*01:01 | 9 | 142 | 56 | binary | 0.525 | 0.810 | 0.520 | 0.807 | - | - | 0.464 | 0.775 | - | - | 0.622 | 0.867 | 0.600 | 0.854 | 0.600 | 0.854 | 0.362 | 0.714 | 0.608 | 0.859 | 0.394 | 0.733 | 0.370 | 0.720 | 0.441 | 0.761 | 0.447 | 0.764 | - | - |
1037480 | HLA-E*01:01 | 9 | 11 | 4 | ic50 | 0.717 | 1.000 | 0.658 | 1.000 | - | - | 0.612 | 1.000 | - | - | 0.461 | 0.964 | 0.553 | 0.964 | 0.575 | 0.964 | 0.484 | 0.821 | 0.553 | 0.964 | 0.466 | 0.786 | 0.658 | 1.000 | 0.690 | 1.000 | 0.603 | 1.000 | - | - |