IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IED for the last at least 3 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
ANN 3.4 74 75 73
ANN 4.0 68 63 73
ARB 11 11 11
IEDB Consensus 62 58 67
NetMHCcons 64 54 75
NetMHCpan 2.8 65 54 76
NetMHCpan 3.0 74 69 80
NetMHCpan 4.0 BA 72 65 80
NetMHCpan 4.0 EL 11 12 9
NetMHCpan 4.1 BA 73 66 81
NetMHCpan 4.1 EL 7 9 6
PickPocket 36 33 38
SMM 60 62 59
SMMPMBEC 55 51 59
mhcflurry 1.2.0 71 71 71

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


IEDB
Reference		 Allele Peptide
Length		 Peptide
Count		 Positive
Count		 Measurement
type		 ANN 3.4 ANN 4.0 ARB IEDB Consensus NetMHCcons NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 BA NetMHCpan 4.0 EL NetMHCpan 4.1 BA NetMHCpan 4.1 EL PickPocket SMM SMMPMBEC mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1037480   HLA-E*01:01   9   142   56   binary   0.525   0.810   0.520   0.807   -   -   0.464   0.775   -   -   0.622   0.867   0.600   0.854   0.600   0.854   0.362   0.714   0.608   0.859   0.394   0.733   0.370   0.720   0.441   0.761   0.447   0.764   -   - 
 1037480   HLA-E*01:01   9   11   4   ic50   0.717   1.000   0.658   1.000   -   -   0.612   1.000   -   -   0.461   0.964   0.553   0.964   0.575   0.964   0.484   0.821   0.553   0.964   0.466   0.786   0.658   1.000   0.690   1.000   0.603   1.000   -   - 
 1037766   HLA-A*02:01   9   82   70   binary   0.462   0.877   0.462   0.877   0.340   0.777   0.451   0.868   0.478   0.890   0.480   0.892   0.504   0.912   0.507   0.914   0.429   0.850   0.497   0.906   0.423   0.845   0.448   0.866   0.440   0.860   0.435   0.855   0.477   0.889 
 1037812   HLA-A*11:01   9   22   9   ic50   0.913   0.974   0.896   0.974   0.875   0.923   0.907   0.974   0.891   0.974   0.891   0.974   0.898   0.983   0.892   0.983   0.788   0.906   0.893   0.983   -0.018   0.538   0.777   0.893   0.936   0.974   0.924   0.974   0.907   0.974