IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IED for the last at least 5 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
ANN 3.4 66 66 67
ANN 4.0 59 56 61
ARB 27 20 34
IEDB Consensus 37 37 37
NetMHCcons 71 67 76
NetMHCpan 2.8 81 83 79
NetMHCpan 3.0 72 70 74
NetMHCpan 4.0 BA 81 71 90
NetMHCpan 4.0 EL 66 61 71
NetMHCpan 4.1 BA 85 83 87
NetMHCpan 4.1 EL 41 34 49
PickPocket 35 36 34
SMM 32 33 31
SMMPMBEC 36 41 31
mhcflurry 1.2.0 66 66 66

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


IEDB
Reference		 Allele Peptide
Length		 Peptide
Count		 Positive
Count		 Measurement
type		 ANN 3.4 ANN 4.0 ARB IEDB Consensus NetMHCcons NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 BA NetMHCpan 4.0 EL NetMHCpan 4.1 BA NetMHCpan 4.1 EL PickPocket SMM SMMPMBEC mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1037971   HLA-B*15:01   9   12   4   ic50   0.552   0.812   0.636   0.875   0.378   0.719   0.476   0.781   0.657   0.875   0.720   0.938   0.692   0.906   0.685   0.906   0.734   0.969   0.685   0.875   0.643   0.906   0.671   0.875   0.490   0.750   0.490   0.750   0.643   0.875 
 1037895   HLA-A*02:01   9   12   8   ic50   0.692   0.750   0.643   0.656   0.643   0.719   0.677   0.703   0.664   0.719   0.692   0.719   0.497   0.656   0.587   0.719   0.182   0.500   0.692   0.719   0.126   0.469   0.503   0.562   0.657   0.688   0.699   0.688   0.790   0.781 
 1037895   HLA-A*02:01   10   11   6   ic50   0.555   0.700   0.573   0.700   0.536   0.767   0.424   0.600   0.636   0.733   0.691   0.733   0.700   0.833   0.573   0.767   0.445   0.700   0.664   0.800   0.409   0.700   0.296   0.550   0.355   0.567   0.355   0.567   0.491   0.600 
 1038020   HLA-A*02:01   9   14   6   t1/2   -0.200   0.396   -0.215   0.396   -0.163   0.458   -0.303   0.354   -0.203   0.375   -0.123   0.417   -0.010   0.479   -0.010   0.479   -0.128   0.375   -0.075   0.438   -0.195   0.312   -0.183   0.417   -0.295   0.354   -0.230   0.396   -0.198   0.417 
 1038478   HLA-A*02:01   9   25   12   binary   0.856   0.994   0.855   0.994   0.811   0.968   0.825   0.974   0.855   0.994   0.844   0.987   0.855   0.994   0.855   0.994   0.855   0.994   0.855   0.994   0.727   0.920   0.827   0.978   0.822   0.974   0.822   0.974   0.833   0.981 
 1038307   HLA-A*02:01   9   10   6   binary   0.711   0.917   0.711   0.917   0.569   0.833   0.711   0.917   0.711   0.917   0.782   0.958   0.711   0.917   0.782   0.958   0.782   0.958   0.782   0.958   0.853   1.000   0.711   0.917   0.711   0.917   0.711   0.917   0.782   0.958