MHCI Weekly Benchmark results
Overall scores
Overall scores based on data sets submitted to the IED for the last at least 12 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.
Server | Overall | SRCC | AUC |
---|---|---|---|
ANN 3.4 | 60 | 59 | 62 |
ANN 4.0 | 64 | 63 | 65 |
ARB | 46 | 44 | 49 |
IEDB Consensus | 65 | 66 | 65 |
NetMHCcons | 60 | 59 | 62 |
NetMHCpan 2.8 | 57 | 56 | 58 |
NetMHCpan 3.0 | 67 | 67 | 67 |
NetMHCpan 4.0 BA | 62 | 63 | 61 |
NetMHCpan 4.0 EL | 43 | 43 | 43 |
NetMHCpan 4.1 BA | 70 | 70 | 70 |
NetMHCpan 4.1 EL | 43 | 43 | 43 |
PickPocket | 55 | 54 | 57 |
SMM | 56 | 55 | 57 |
SMMPMBEC | 63 | 61 | 66 |
mhcflurry 1.2.0 | 52 | 51 | 53 |
Data set specific results
Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here
Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.
IEDB Reference |
Allele | Peptide Length |
Peptide Count |
Positive Count |
Measurement type |
ANN 3.4 | ANN 4.0 | ARB | IEDB Consensus | NetMHCcons | NetMHCpan 2.8 | NetMHCpan 3.0 | NetMHCpan 4.0 BA | NetMHCpan 4.0 EL | NetMHCpan 4.1 BA | NetMHCpan 4.1 EL | PickPocket | SMM | SMMPMBEC | mhcflurry 1.2.0 | |||||||||||||||
SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | ||||||
1039752 | HLA-A*03:01 | 9 | 24 | 16 | ic50 | 0.236 | 0.641 | 0.196 | 0.586 | 0.351 | 0.672 | 0.187 | 0.488 | 0.251 | 0.648 | 0.217 | 0.625 | 0.272 | 0.594 | 0.262 | 0.625 | 0.471 | 0.727 | 0.278 | 0.648 | - | - | -0.056 | 0.500 | 0.083 | 0.395 | 0.085 | 0.406 | 0.222 | 0.539 |
1039752 | HLA-B*27:05 | 9 | 25 | 21 | ic50 | 0.411 | 0.851 | 0.316 | 0.690 | 0.054 | 0.750 | 0.481 | 0.690 | 0.445 | 0.869 | 0.438 | 0.810 | 0.359 | 0.726 | 0.486 | 0.702 | 0.146 | 0.524 | 0.279 | 0.643 | 0.147 | 0.565 | 0.071 | 0.548 | 0.458 | 0.869 | 0.394 | 0.917 | 0.217 | 0.714 |
1040276 | HLA-A*02:01 | 9 | 21 | 14 | binary | 0.551 | 0.837 | 0.500 | 0.806 | 0.367 | 0.724 | 0.393 | 0.755 | 0.551 | 0.837 | 0.534 | 0.827 | 0.500 | 0.806 | 0.500 | 0.806 | 0.350 | 0.714 | 0.551 | 0.837 | 0.350 | 0.714 | 0.450 | 0.776 | 0.392 | 0.750 | 0.467 | 0.786 | 0.150 | 0.592 |
1040276 | HLA-A*02:01 | 10 | 11 | 7 | binary | -0.060 | 0.464 | 0.179 | 0.607 | 0.060 | 0.536 | 0.120 | 0.571 | -0.120 | 0.429 | -0.120 | 0.429 | 0.418 | 0.750 | 0.179 | 0.607 | 0.060 | 0.536 | 0.179 | 0.607 | 0.120 | 0.571 | -0.299 | 0.321 | 0.000 | 0.500 | 0.000 | 0.500 | -0.179 | 0.393 |
1038337 | HLA-A*26:01 | 9 | 13 | 2 | binary | -0.057 | 0.455 | 0.057 | 0.545 | -0.171 | 0.364 | -0.171 | 0.364 | -0.114 | 0.409 | -0.114 | 0.409 | -0.228 | 0.318 | 0.000 | 0.500 | -0.114 | 0.409 | -0.057 | 0.455 | -0.285 | 0.273 | -0.456 | 0.136 | -0.342 | 0.227 | -0.228 | 0.318 | 0.057 | 0.545 |
1038337 | HLA-A*26:01 | 10 | 11 | 2 | binary | 0.075 | 0.556 | 0.149 | 0.611 | -0.037 | 0.667 | 0.187 | 0.806 | 0.000 | 0.500 | 0.000 | 0.500 | 0.149 | 0.611 | 0.224 | 0.667 | -0.149 | 0.389 | 0.224 | 0.667 | -0.037 | 0.500 | 0.157 | 0.750 | 0.298 | 0.722 | 0.149 | 0.611 | 0.298 | 0.722 |
1016643 | HLA-A*02:01 | 9 | 14 | 9 | binary | 0.759 | 0.956 | 0.832 | 1.000 | 0.721 | 0.933 | 0.834 | 1.000 | 0.795 | 0.978 | 0.795 | 0.978 | 0.832 | 1.000 | 0.832 | 1.000 | 0.721 | 0.933 | 0.832 | 1.000 | 0.721 | 0.933 | 0.795 | 0.978 | 0.832 | 1.000 | 0.832 | 1.000 | 0.795 | 0.978 |
1040736 | HLA-C*08:02 | 9 | 17 | 14 | binary | 0.567 | 0.929 | 0.598 | 0.952 | - | - | 0.584 | 0.940 | 0.630 | 0.976 | 0.630 | 0.976 | 0.630 | 0.976 | 0.598 | 0.952 | 0.598 | 0.952 | 0.598 | 0.952 | 0.567 | 0.929 | 0.661 | 1.000 | 0.505 | 0.881 | 0.661 | 1.000 | 0.504 | 0.881 |
1041184 | HLA-A*24:02 | 9 | 12 | 10 | binary | 0.324 | 0.750 | 0.389 | 0.800 | 0.324 | 0.750 | 0.423 | 0.850 | 0.194 | 0.650 | 0.194 | 0.650 | 0.259 | 0.700 | 0.324 | 0.750 | -0.259 | 0.300 | 0.389 | 0.800 | -0.259 | 0.300 | 0.324 | 0.750 | 0.389 | 0.800 | 0.453 | 0.850 | 0.518 | 0.900 |
1040281 | HLA-A*01:01 | 9 | 16 | 2 | binary | 0.574 | 1.000 | 0.574 | 1.000 | 0.574 | 1.000 | 0.575 | 1.000 | 0.574 | 1.000 | 0.574 | 1.000 | 0.574 | 1.000 | 0.574 | 1.000 | - | - | 0.574 | 1.000 | 0.574 | 1.000 | 0.578 | 1.000 | 0.574 | 1.000 | 0.574 | 1.000 | 0.574 | 1.000 |
1040281 | HLA-A*02:01 | 9 | 16 | 10 | binary | 0.448 | 0.767 | 0.504 | 0.800 | 0.476 | 0.783 | 0.406 | 0.750 | 0.392 | 0.733 | 0.448 | 0.767 | 0.392 | 0.733 | 0.392 | 0.733 | - | - | 0.392 | 0.733 | 0.448 | 0.767 | 0.519 | 0.808 | 0.448 | 0.767 | 0.448 | 0.767 | 0.392 | 0.733 |
1040281 | HLA-A*02:03 | 9 | 16 | 7 | binary | 0.342 | 0.698 | 0.424 | 0.746 | 0.424 | 0.746 | 0.396 | 0.730 | 0.424 | 0.746 | 0.533 | 0.810 | 0.506 | 0.794 | 0.506 | 0.794 | 0.533 | 0.810 | 0.506 | 0.794 | 0.506 | 0.794 | 0.506 | 0.794 | 0.342 | 0.698 | 0.342 | 0.698 | 0.451 | 0.762 |
1040281 | HLA-A*03:01 | 9 | 16 | 4 | binary | 0.595 | 0.896 | 0.626 | 0.917 | 0.532 | 0.854 | 0.626 | 0.917 | 0.564 | 0.875 | 0.564 | 0.875 | 0.470 | 0.812 | 0.470 | 0.812 | 0.438 | 0.792 | 0.532 | 0.854 | 0.470 | 0.812 | 0.220 | 0.646 | 0.501 | 0.833 | 0.532 | 0.854 | 0.470 | 0.812 |
1040281 | HLA-A*11:01 | 9 | 16 | 3 | binary | 0.261 | 0.692 | 0.261 | 0.692 | 0.330 | 0.744 | 0.226 | 0.718 | 0.191 | 0.641 | 0.191 | 0.641 | 0.295 | 0.718 | 0.122 | 0.590 | -0.191 | 0.359 | 0.052 | 0.538 | 0.087 | 0.564 | 0.435 | 0.821 | 0.261 | 0.692 | 0.191 | 0.641 | 0.365 | 0.769 |
1040281 | HLA-A*23:01 | 9 | 16 | 6 | binary | 0.756 | 0.950 | 0.812 | 0.983 | 0.756 | 0.950 | 0.812 | 0.983 | 0.812 | 0.983 | 0.840 | 1.000 | 0.840 | 1.000 | 0.812 | 0.983 | 0.588 | 0.850 | 0.812 | 0.983 | 0.420 | 0.750 | 0.785 | 0.967 | 0.812 | 0.983 | 0.784 | 0.967 | 0.784 | 0.967 |
1040281 | HLA-A*24:02 | 9 | 16 | 3 | binary | 0.156 | 0.615 | 0.122 | 0.590 | -0.017 | 0.487 | 0.156 | 0.615 | 0.122 | 0.590 | 0.156 | 0.615 | 0.191 | 0.641 | 0.191 | 0.641 | 0.191 | 0.641 | 0.226 | 0.667 | 0.052 | 0.538 | 0.017 | 0.513 | 0.087 | 0.564 | 0.122 | 0.590 | 0.156 | 0.615 |
1040281 | HLA-A*31:01 | 9 | 16 | 2 | binary | 0.123 | 0.607 | 0.082 | 0.571 | 0.041 | 0.536 | 0.164 | 0.643 | - | - | -0.123 | 0.393 | 0.000 | 0.500 | 0.000 | 0.500 | -0.082 | 0.429 | -0.041 | 0.464 | -0.164 | 0.357 | 0.000 | 0.500 | 0.164 | 0.643 | - | - | 0.041 | 0.536 |
1040281 | HLA-B*15:01 | 9 | 16 | 7 | binary | 0.260 | 0.651 | 0.396 | 0.730 | 0.041 | 0.524 | 0.343 | 0.698 | 0.328 | 0.690 | 0.451 | 0.762 | 0.478 | 0.778 | 0.424 | 0.746 | 0.506 | 0.794 | 0.424 | 0.746 | 0.506 | 0.794 | 0.438 | 0.762 | 0.287 | 0.667 | 0.287 | 0.667 | 0.287 | 0.667 |
1040281 | HLA-B*40:01 | 9 | 16 | 2 | binary | 0.574 | 1.000 | 0.574 | 1.000 | 0.369 | 0.821 | 0.576 | 1.000 | 0.574 | 1.000 | 0.574 | 1.000 | 0.574 | 1.000 | 0.574 | 1.000 | 0.451 | 0.893 | 0.574 | 1.000 | 0.410 | 0.857 | 0.574 | 1.000 | 0.574 | 1.000 | - | - | 0.574 | 1.000 |
1040281 | HLA-B*44:02 | 9 | 16 | 7 | binary | -0.342 | 0.302 | -0.342 | 0.302 | -0.369 | 0.286 | -0.342 | 0.302 | -0.369 | 0.286 | -0.451 | 0.238 | -0.178 | 0.397 | -0.287 | 0.333 | -0.123 | 0.429 | -0.396 | 0.270 | 0.150 | 0.587 | -0.150 | 0.413 | -0.424 | 0.254 | -0.314 | 0.317 | -0.287 | 0.333 |
1040281 | HLA-B*44:03 | 9 | 16 | 2 | binary | -0.287 | 0.250 | -0.164 | 0.357 | -0.208 | 0.375 | -0.369 | 0.179 | -0.308 | 0.250 | -0.246 | 0.286 | 0.041 | 0.536 | - | - | -0.410 | 0.143 | -0.205 | 0.321 | -0.328 | 0.214 | 0.082 | 0.571 | -0.574 | 0.000 | -0.246 | 0.286 | -0.164 | 0.357 |
1041542 | HLA-A*02:01 | 9 | 34 | 26 | binary | 0.329 | 0.724 | 0.325 | 0.721 | 0.325 | 0.721 | 0.330 | 0.724 | 0.325 | 0.721 | 0.325 | 0.721 | 0.339 | 0.731 | 0.318 | 0.716 | 0.481 | 0.827 | 0.339 | 0.731 | 0.509 | 0.846 | 0.290 | 0.697 | 0.318 | 0.716 | 0.318 | 0.716 | 0.318 | 0.716 |
1041542 | HLA-A*11:01 | 9 | 12 | 10 | binary | 0.650 | 1.000 | 0.518 | 0.900 | 0.648 | 1.000 | 0.584 | 0.950 | 0.648 | 1.000 | 0.389 | 0.800 | 0.453 | 0.850 | 0.453 | 0.850 | 0.583 | 0.950 | 0.518 | 0.900 | 0.518 | 0.900 | 0.649 | 1.000 | 0.583 | 0.950 | 0.648 | 1.000 | 0.518 | 0.900 |
1032718 | HLA-A*02:01 | 10 | 10 | 2 | binary | 0.522 | 0.875 | 0.435 | 0.812 | 0.696 | 1.000 | 0.524 | 0.875 | 0.435 | 0.812 | 0.348 | 0.750 | 0.522 | 0.875 | 0.522 | 0.875 | 0.087 | 0.562 | 0.435 | 0.812 | 0.087 | 0.562 | 0.522 | 0.875 | 0.522 | 0.875 | 0.522 | 0.875 | 0.522 | 0.875 |
1042224 | H-2-Db | 10 | 57 | 33 | binary | 0.572 | 0.835 | 0.460 | 0.769 | 0.475 | 0.778 | 0.538 | 0.814 | 0.532 | 0.812 | 0.503 | 0.794 | 0.408 | 0.739 | 0.458 | 0.768 | 0.436 | 0.755 | 0.488 | 0.785 | 0.517 | 0.802 | 0.431 | 0.753 | 0.510 | 0.798 | 0.572 | 0.835 | 0.540 | 0.816 |
1042224 | H-2-Kb | 10 | 57 | 20 | binary | 0.599 | 0.862 | 0.704 | 0.926 | 0.594 | 0.859 | 0.696 | 0.924 | 0.610 | 0.869 | 0.545 | 0.830 | 0.706 | 0.927 | 0.715 | 0.932 | 0.686 | 0.915 | 0.715 | 0.932 | 0.708 | 0.928 | 0.409 | 0.747 | 0.608 | 0.868 | 0.623 | 0.877 | 0.617 | 0.873 |
1042276 | HLA-A*02:01 | 9 | 345 | 198 | binary | -0.029 | 0.483 | -0.035 | 0.480 | -0.044 | 0.474 | -0.037 | 0.479 | -0.043 | 0.476 | -0.051 | 0.470 | -0.026 | 0.485 | -0.023 | 0.487 | -0.045 | 0.474 | -0.025 | 0.485 | -0.007 | 0.497 | -0.006 | 0.497 | -0.030 | 0.483 | -0.026 | 0.485 | -0.051 | 0.470 |
1042273 | HLA-A*23:01 | 9 | 17 | 14 | binary | 0.158 | 0.619 | 0.220 | 0.667 | 0.315 | 0.738 | 0.189 | 0.643 | 0.189 | 0.643 | 0.189 | 0.643 | 0.157 | 0.619 | 0.157 | 0.619 | 0.205 | 0.655 | 0.220 | 0.667 | 0.221 | 0.667 | 0.252 | 0.690 | 0.189 | 0.643 | 0.220 | 0.667 | 0.220 | 0.667 |
1042273 | HLA-A*68:01 | 9 | 15 | 10 | binary | 0.655 | 0.900 | 0.655 | 0.900 | 0.624 | 0.880 | 0.655 | 0.900 | 0.655 | 0.900 | 0.589 | 0.860 | 0.622 | 0.880 | 0.589 | 0.860 | -0.033 | 0.480 | 0.589 | 0.860 | 0.327 | 0.700 | 0.655 | 0.900 | 0.622 | 0.880 | 0.655 | 0.900 | 0.655 | 0.900 |
1042273 | HLA-B*07:02 | 9 | 19 | 15 | binary | 0.707 | 1.000 | 0.684 | 0.983 | 0.684 | 0.983 | 0.685 | 0.983 | 0.707 | 1.000 | 0.707 | 1.000 | 0.707 | 1.000 | 0.707 | 1.000 | 0.707 | 1.000 | 0.707 | 1.000 | 0.707 | 1.000 | 0.637 | 0.950 | 0.707 | 1.000 | 0.707 | 1.000 | 0.613 | 0.933 |
1042273 | HLA-B*08:01 | 9 | 23 | 20 | binary | 0.487 | 0.917 | 0.467 | 0.900 | 0.370 | 0.817 | 0.470 | 0.900 | 0.467 | 0.900 | 0.506 | 0.933 | 0.525 | 0.950 | 0.467 | 0.900 | 0.487 | 0.917 | 0.487 | 0.917 | 0.448 | 0.883 | 0.526 | 0.950 | 0.467 | 0.900 | 0.467 | 0.900 | 0.467 | 0.900 |