MHCI Weekly Benchmark results
Overall scores
Overall scores based on data sets submitted to the IED for the last at least 5 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.
Server | Overall | SRCC | AUC |
---|---|---|---|
ANN 3.4 | 66 | 63 | 69 |
ANN 4.0 | 55 | 50 | 61 |
ARB | 34 | 34 | 33 |
IEDB Consensus | 52 | 48 | 57 |
NetMHCcons | 70 | 70 | 70 |
NetMHCpan 2.8 | 65 | 64 | 66 |
NetMHCpan 3.0 | 65 | 62 | 69 |
NetMHCpan 4.0 BA | 66 | 65 | 67 |
NetMHCpan 4.0 EL | 42 | 38 | 46 |
NetMHCpan 4.1 BA | 74 | 72 | 77 |
NetMHCpan 4.1 EL | 32 | 30 | 33 |
PickPocket | 40 | 43 | 36 |
SMM | 51 | 49 | 53 |
SMMPMBEC | 56 | 54 | 57 |
mhcflurry 1.2.0 | 56 | 53 | 59 |
Data set specific results
Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here
Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.
IEDB Reference |
Allele | Peptide Length |
Peptide Count |
Positive Count |
Measurement type |
ANN 3.4 | ANN 4.0 | ARB | IEDB Consensus | NetMHCcons | NetMHCpan 2.8 | NetMHCpan 3.0 | NetMHCpan 4.0 BA | NetMHCpan 4.0 EL | NetMHCpan 4.1 BA | NetMHCpan 4.1 EL | PickPocket | SMM | SMMPMBEC | mhcflurry 1.2.0 | |||||||||||||||
SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | ||||||
1042273 | HLA-A*23:01 | 9 | 17 | 14 | binary | 0.158 | 0.619 | 0.220 | 0.667 | 0.315 | 0.738 | 0.189 | 0.643 | 0.189 | 0.643 | 0.189 | 0.643 | 0.157 | 0.619 | 0.157 | 0.619 | 0.205 | 0.655 | 0.220 | 0.667 | 0.221 | 0.667 | 0.252 | 0.690 | 0.189 | 0.643 | 0.220 | 0.667 | 0.220 | 0.667 |
1042273 | HLA-A*68:01 | 9 | 15 | 10 | binary | 0.655 | 0.900 | 0.655 | 0.900 | 0.624 | 0.880 | 0.655 | 0.900 | 0.655 | 0.900 | 0.589 | 0.860 | 0.622 | 0.880 | 0.589 | 0.860 | -0.033 | 0.480 | 0.589 | 0.860 | 0.327 | 0.700 | 0.655 | 0.900 | 0.622 | 0.880 | 0.655 | 0.900 | 0.655 | 0.900 |
1042273 | HLA-B*07:02 | 9 | 19 | 15 | binary | 0.707 | 1.000 | 0.684 | 0.983 | 0.684 | 0.983 | 0.685 | 0.983 | 0.707 | 1.000 | 0.707 | 1.000 | 0.707 | 1.000 | 0.707 | 1.000 | 0.707 | 1.000 | 0.707 | 1.000 | 0.707 | 1.000 | 0.637 | 0.950 | 0.707 | 1.000 | 0.707 | 1.000 | 0.613 | 0.933 |
1042273 | HLA-B*08:01 | 9 | 23 | 20 | binary | 0.487 | 0.917 | 0.467 | 0.900 | 0.370 | 0.817 | 0.470 | 0.900 | 0.467 | 0.900 | 0.506 | 0.933 | 0.525 | 0.950 | 0.467 | 0.900 | 0.487 | 0.917 | 0.487 | 0.917 | 0.448 | 0.883 | 0.526 | 0.950 | 0.467 | 0.900 | 0.467 | 0.900 | 0.467 | 0.900 |
1042741 | HLA-A*02:01 | 9 | 18 | 2 | binary | 0.477 | 0.938 | 0.443 | 0.906 | 0.477 | 0.938 | 0.443 | 0.906 | 0.443 | 0.906 | 0.443 | 0.906 | 0.341 | 0.812 | 0.341 | 0.812 | 0.409 | 0.875 | 0.375 | 0.844 | 0.460 | 0.922 | 0.307 | 0.781 | 0.443 | 0.906 | 0.477 | 0.938 | 0.477 | 0.938 |
1042741 | HLA-A*02:01 | 10 | 22 | 7 | binary | 0.638 | 0.895 | 0.654 | 0.905 | 0.731 | 0.952 | 0.754 | 0.971 | 0.685 | 0.924 | 0.669 | 0.914 | 0.669 | 0.914 | 0.638 | 0.895 | 0.423 | 0.762 | 0.638 | 0.895 | 0.231 | 0.643 | 0.701 | 0.933 | 0.731 | 0.952 | 0.761 | 0.971 | 0.561 | 0.848 |
1042741 | HLA-A*11:01 | 10 | 26 | 17 | binary | 0.631 | 0.882 | 0.749 | 0.954 | 0.685 | 0.915 | 0.717 | 0.935 | 0.652 | 0.895 | 0.674 | 0.908 | 0.760 | 0.961 | 0.738 | 0.948 | 0.523 | 0.817 | 0.728 | 0.941 | 0.016 | 0.510 | 0.507 | 0.810 | 0.684 | 0.915 | 0.706 | 0.928 | 0.663 | 0.902 |
1042741 | HLA-A*24:02 | 9 | 10 | 8 | binary | 0.609 | 0.938 | 0.435 | 0.812 | 0.435 | 0.812 | 0.522 | 0.875 | 0.609 | 0.938 | 0.609 | 0.938 | 0.435 | 0.812 | 0.435 | 0.812 | 0.435 | 0.812 | 0.609 | 0.938 | -0.174 | 0.375 | 0.609 | 0.938 | 0.609 | 0.938 | 0.522 | 0.875 | 0.435 | 0.812 |
1042741 | HLA-A*24:02 | 10 | 10 | 5 | binary | 0.661 | 0.880 | 0.870 | 1.000 | 0.731 | 0.920 | 0.731 | 0.920 | 0.731 | 0.920 | 0.731 | 0.920 | 0.870 | 1.000 | 0.870 | 1.000 | 0.768 | 0.940 | 0.870 | 1.000 | 0.244 | 0.640 | 0.803 | 0.960 | 0.522 | 0.800 | 0.731 | 0.920 | 0.661 | 0.880 |
1042741 | HLA-A*33:03 | 9 | 20 | 4 | binary | - | - | - | - | - | - | - | - | 0.672 | 0.984 | 0.672 | 0.984 | 0.694 | 1.000 | 0.694 | 1.000 | 0.650 | 0.969 | 0.694 | 1.000 | 0.564 | 0.906 | 0.412 | 0.820 | - | - | - | - | - | - |
1042741 | HLA-A*33:03 | 10 | 28 | 6 | binary | - | - | - | - | - | - | - | - | 0.571 | 0.902 | 0.571 | 0.902 | 0.625 | 0.939 | 0.625 | 0.939 | 0.420 | 0.795 | 0.657 | 0.962 | 0.237 | 0.667 | 0.459 | 0.822 | - | - | - | - | - | - |
1042685 | HLA-A*02:01 | 9 | 196 | 164 | binary | 0.532 | 0.915 | 0.529 | 0.913 | 0.516 | 0.903 | 0.509 | 0.897 | 0.536 | 0.919 | 0.535 | 0.918 | 0.532 | 0.915 | 0.534 | 0.917 | 0.522 | 0.907 | 0.534 | 0.917 | 0.517 | 0.904 | 0.530 | 0.914 | 0.522 | 0.908 | 0.525 | 0.910 | 0.529 | 0.913 |
1042344 | HLA-A*02:01 | 9 | 12 | 10 | binary | 0.324 | 0.750 | 0.389 | 0.800 | 0.065 | 0.550 | 0.162 | 0.625 | 0.194 | 0.650 | 0.130 | 0.600 | 0.259 | 0.700 | 0.259 | 0.700 | 0.130 | 0.600 | 0.259 | 0.700 | 0.065 | 0.550 | 0.196 | 0.650 | 0.130 | 0.600 | 0.130 | 0.600 | 0.259 | 0.700 |
1042751 | HLA-A*01:01 | 9 | 17 | 15 | ic50 | 0.799 | 0.967 | 0.816 | 1.000 | 0.644 | 0.767 | 0.796 | 1.000 | 0.830 | 0.967 | 0.826 | 1.000 | 0.749 | 0.900 | 0.764 | 0.867 | 0.511 | 0.767 | 0.717 | 0.933 | 0.592 | 0.767 | 0.634 | 0.833 | 0.757 | 0.967 | 0.700 | 0.900 | 0.759 | 0.933 |
1042751 | HLA-A*01:01 | 10 | 10 | 8 | ic50 | 0.939 | 1.000 | 0.818 | 1.000 | 0.867 | 0.875 | 0.717 | 0.875 | 0.952 | 0.938 | 0.952 | 0.938 | 0.806 | 0.875 | 0.818 | 0.875 | 0.744 | 0.875 | 0.879 | 1.000 | 0.842 | 1.000 | 0.879 | 0.812 | 0.697 | 0.812 | 0.782 | 0.750 | 0.903 | 0.938 |
1042751 | HLA-A*02:01 | 9 | 107 | 96 | ic50 | 0.742 | 0.841 | 0.738 | 0.839 | 0.613 | 0.739 | 0.651 | 0.787 | 0.754 | 0.834 | 0.746 | 0.820 | 0.787 | 0.837 | 0.779 | 0.827 | 0.679 | 0.772 | 0.792 | 0.833 | 0.673 | 0.813 | 0.584 | 0.753 | 0.685 | 0.806 | 0.696 | 0.820 | 0.714 | 0.800 |
1042751 | HLA-A*02:01 | 10 | 65 | 46 | ic50 | 0.745 | 0.892 | 0.684 | 0.858 | 0.582 | 0.835 | 0.700 | 0.886 | 0.751 | 0.892 | 0.743 | 0.890 | 0.682 | 0.854 | 0.673 | 0.851 | 0.587 | 0.815 | 0.670 | 0.846 | 0.569 | 0.773 | 0.655 | 0.847 | 0.630 | 0.842 | 0.618 | 0.850 | 0.702 | 0.857 |
1042751 | HLA-A*02:01 | 11 | 17 | 14 | ic50 | -0.002 | 0.333 | -0.170 | 0.500 | -0.411 | 0.048 | 0.191 | 0.500 | 0.071 | 0.286 | 0.142 | 0.333 | 0.001 | 0.690 | 0.134 | 0.762 | 0.455 | 0.810 | 0.269 | 0.833 | 0.310 | 0.786 | 0.112 | 0.286 | 0.465 | 0.690 | 0.281 | 0.571 | 0.103 | 0.357 |
1042751 | HLA-A*03:01 | 9 | 19 | 14 | ic50 | 0.769 | 0.914 | 0.751 | 0.943 | 0.537 | 0.871 | 0.755 | 0.943 | 0.756 | 0.929 | 0.761 | 0.957 | 0.749 | 0.957 | 0.739 | 0.957 | 0.575 | 0.886 | 0.744 | 0.957 | 0.646 | 0.914 | 0.715 | 0.879 | 0.751 | 0.943 | 0.739 | 0.929 | 0.723 | 0.986 |
1042751 | HLA-A*03:01 | 10 | 23 | 13 | ic50 | 0.888 | 0.969 | 0.799 | 0.838 | 0.805 | 0.854 | 0.878 | 0.908 | 0.855 | 0.954 | 0.806 | 0.908 | 0.734 | 0.777 | 0.743 | 0.777 | 0.629 | 0.777 | 0.711 | 0.754 | 0.621 | 0.762 | 0.723 | 0.846 | 0.863 | 0.908 | 0.850 | 0.908 | 0.847 | 0.962 |
1042751 | HLA-A*11:01 | 9 | 12 | 9 | ic50 | 0.692 | 1.000 | 0.699 | 1.000 | 0.727 | 0.963 | 0.669 | 1.000 | 0.706 | 1.000 | 0.720 | 1.000 | 0.867 | 1.000 | 0.867 | 1.000 | 0.797 | 1.000 | 0.839 | 1.000 | 0.727 | 0.963 | 0.790 | 0.889 | 0.699 | 1.000 | 0.699 | 1.000 | 0.720 | 1.000 |
1042751 | HLA-A*11:01 | 10 | 18 | 10 | ic50 | 0.882 | 0.938 | 0.678 | 0.850 | 0.445 | 0.775 | 0.765 | 0.912 | 0.874 | 0.900 | 0.845 | 0.875 | 0.781 | 0.887 | 0.827 | 0.938 | 0.707 | 0.912 | 0.833 | 0.950 | 0.717 | 0.887 | 0.567 | 0.750 | 0.750 | 0.912 | 0.744 | 0.887 | 0.934 | 0.988 |
1042751 | HLA-A*24:02 | 9 | 13 | 10 | ic50 | 0.665 | 0.833 | 0.599 | 0.833 | 0.571 | 0.733 | 0.708 | 0.833 | 0.692 | 0.867 | 0.648 | 0.867 | 0.604 | 0.867 | 0.742 | 0.900 | 0.824 | 0.900 | 0.747 | 0.900 | 0.828 | 0.883 | 0.764 | 0.767 | 0.703 | 0.767 | 0.670 | 0.767 | 0.659 | 0.800 |
1042751 | HLA-A*24:02 | 10 | 10 | 6 | ic50 | 0.818 | 0.875 | 0.491 | 0.750 | 0.830 | 0.875 | 0.794 | 0.875 | 0.842 | 0.875 | 0.794 | 0.833 | 0.564 | 0.833 | 0.515 | 0.750 | 0.479 | 0.833 | 0.636 | 0.833 | 0.321 | 0.792 | 0.818 | 0.792 | 0.842 | 0.875 | 0.903 | 0.958 | 0.806 | 0.833 |
1042751 | HLA-A*68:01 | 10 | 11 | 9 | ic50 | 0.482 | 0.833 | 0.327 | 0.778 | 0.255 | 0.667 | 0.497 | 0.833 | 0.574 | 0.833 | 0.545 | 0.833 | 0.545 | 0.889 | 0.573 | 0.833 | 0.700 | 0.889 | 0.618 | 0.889 | 0.518 | 0.722 | 0.364 | 0.778 | 0.573 | 0.889 | 0.555 | 0.889 | 0.491 | 0.778 |
1042751 | HLA-B*07:02 | 9 | 11 | 9 | ic50 | 0.473 | 0.778 | 0.409 | 0.722 | 0.527 | 0.833 | 0.406 | 0.611 | 0.527 | 0.833 | 0.509 | 0.833 | 0.691 | 0.778 | 0.591 | 0.833 | 0.318 | 0.833 | 0.673 | 0.833 | 0.427 | 0.833 | 0.191 | 0.611 | 0.318 | 0.556 | 0.518 | 0.722 | 0.518 | 0.778 |
1042751 | HLA-B*08:01 | 9 | 26 | 23 | ic50 | 0.649 | 0.696 | 0.627 | 0.696 | 0.529 | 0.652 | 0.507 | 0.667 | 0.669 | 0.703 | 0.664 | 0.696 | 0.711 | 0.783 | 0.749 | 0.884 | -0.023 | 0.420 | 0.723 | 0.797 | 0.109 | 0.464 | 0.295 | 0.471 | 0.518 | 0.667 | 0.572 | 0.696 | 0.599 | 0.739 |
1042751 | HLA-B*44:02 | 9 | 17 | 8 | ic50 | 0.444 | 0.625 | 0.647 | 0.708 | 0.029 | 0.347 | 0.313 | 0.549 | 0.395 | 0.569 | 0.343 | 0.542 | 0.559 | 0.681 | 0.559 | 0.653 | 0.387 | 0.542 | 0.571 | 0.653 | 0.405 | 0.549 | 0.301 | 0.514 | 0.245 | 0.500 | 0.206 | 0.458 | 0.480 | 0.681 |
1042751 | HLA-B*44:02 | 10 | 19 | 7 | ic50 | 0.739 | 0.821 | 0.635 | 0.810 | 0.521 | 0.690 | 0.683 | 0.774 | 0.796 | 0.893 | 0.807 | 0.905 | 0.781 | 0.857 | 0.853 | 0.905 | 0.858 | 0.893 | 0.812 | 0.869 | 0.793 | 0.857 | 0.807 | 0.893 | 0.698 | 0.774 | 0.668 | 0.750 | 0.725 | 0.833 |