IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
ANN 3.4 85 85 85
ANN 4.0 40 40 40
ARB 0 0 0
IEDB Consensus 85 85 85
NetMHCcons 65 65 65
NetMHCpan 2.8 60 60 60
NetMHCpan 3.0 65 65 65
NetMHCpan 4.0 BA - - -
NetMHCpan 4.0 EL - - -
NetMHCpan 4.1 BA - - -
NetMHCpan 4.1 EL - - -
PickPocket 85 85 85
SMM 85 85 85
SMMPMBEC 90 90 90
mhcflurry 1.2.0 10 10 10

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference		 Allele Peptide
Length		 Peptide
Count		 Positive
Count		 Measurement
type		 ANN 3.4 ANN 4.0 ARB IEDB Consensus NetMHCcons NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 BA NetMHCpan 4.0 EL NetMHCpan 4.1 BA NetMHCpan 4.1 EL PickPocket SMM SMMPMBEC mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 315312   HLA-A*31:01   9   10   4   binary   0.711   0.917   0.711   0.917   0.640   0.875   0.711   0.917   0.711   0.917   0.711   0.917   0.782   0.958   -   -   -   -   -   -   -   -   0.711   0.917   0.711   0.917   0.711   0.917   -   - 
 315312   HLA-A*66:01   9   16   14   binary   0.205   0.679   -0.287   0.250   -   -   0.205   0.679   0.123   0.607   0.041   0.536   0.041   0.536   -   -   -   -   -   -   -   -   0.205   0.679   0.205   0.679   0.574   1.000   -0.123   0.393