IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
NetMHCpan 2.8 22 19 25
NetMHCpan 3.0 60 58 61
NetMHCpan 4.0 75 72 78
SMM 61 64 58
ANN 3.4 43 50 36
ANN 4.0 94 94 94
ARB 50 33 67
SMMPMBEC 51 53 50
IEDB Consensus 63 47 78
NetMHCcons 49 28 69
PickPocket 32 28 36
mhcflurry 1.2.0 90 92 89
DeepSeqPa 8 13 4

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 SMM ANN 3.4 ANN 4.0 ARB SMMPMBEC IEDB Consensus NetMHCcons PickPocket mhcflurry 1.2.0 DeepSeqPa
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1031072   HLA-A*02:01   9   28   23   ic50   0.802   0.983   0.852   0.991   0.875   1.000   0.862   0.991   0.841   0.983   0.887   1.000   0.847   1.000   0.861   0.991   0.828   0.991   0.837   0.991   0.799   0.974   0.888   1.000   0.824   0.957 
 1031072   HLA-A*02:01   10   16   13   ic50   0.850   0.949   0.835   0.923   0.879   0.949   0.718   0.872   0.756   0.872   0.841   0.923   0.609   0.692   0.709   0.872   0.805   0.872   0.771   0.872   0.712   0.821   0.691   0.821   -   - 
 1033576   HLA-A*02:01   9   191   13   binary   0.112   0.628   0.116   0.633   0.113   0.630   0.112   0.632   0.121   0.638   0.147   0.668   0.063   0.573   0.110   0.626   0.130   0.678   0.109   0.652   0.125   0.670   0.123   0.641   0.097   0.611