IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
NetMHCpan 2.8 69 67 71
NetMHCpan 3.0 - - -
NetMHCpan 4.0 57 57 57
SMM 48 48 48
ANN 3.4 - - -
ANN 4.0 69 67 71
ARB - - -
SMMPMBEC 33 24 43
IEDB Consensus 55 48 62
NetMHCcons 74 62 86
PickPocket 36 33 38
mhcflurry 1.2.0 - - -
DeepSeqPa - - -

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 SMM ANN 3.4 ANN 4.0 ARB SMMPMBEC IEDB Consensus NetMHCcons PickPocket mhcflurry 1.2.0 DeepSeqPa
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1037480   HLA-E*01:01   9   142   56   binary   0.622   0.867   -   -   0.600   0.854   0.441   0.761   -   -   0.520   0.807   -   -   0.447   0.764   0.464   0.775   0.576   0.841   0.370   0.720   -   -   -   - 
 1037762   HLA-E*01:01   9   69   43   binary   0.146   0.587   -   -   0.071   0.542   0.013   0.509   -   -   0.059   0.535   -   -   -0.081   0.452   0.038   0.523   0.078   0.547   -0.052   0.471   -   -   -   -