Automated Server Benchmarks

MHCI Weekly Benchmark results

Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.

Server	Overall	SRCC	AUC
ANN 3.4	55	39	71
ANN 4.0	95	89	100
ARB	61	57	64
IEDB Consensus	86	71	100
NetMHCcons	50	50	50
NetMHCpan 2.8	43	50	36
NetMHCpan 3.0	57	61	54
NetMHCpan 4.0 BA	54	57	50
NetMHCpan 4.0 EL	37	43	32
NetMHCpan 4.1 BA	73	82	64
NetMHCpan 4.1 EL	27	4	50
PickPocket	30	4	57
SMM	84	68	100
SMMPMBEC	63	46	79
mhcflurry 1.2.0	46	43	50

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB Reference	Allele	Peptide Length	Peptide Count	Positive Count	Measurement type	ANN 3.4		ANN 4.0		ARB		IEDB Consensus		NetMHCcons		NetMHCpan 2.8		NetMHCpan 3.0		NetMHCpan 4.0 BA		NetMHCpan 4.0 EL		NetMHCpan 4.1 BA		NetMHCpan 4.1 EL		PickPocket		SMM		SMMPMBEC		mhcflurry 1.2.0
IEDB Reference	Allele	Peptide Length	Peptide Count	Positive Count	Measurement type	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC
1045240	HLA-A*02:01	10	11	2	ic50	0.050	0.944	0.241	1.000	0.155	1.000	0.100	1.000	0.109	0.944	0.182	0.944	0.369	1.000	0.396	1.000	-0.064	0.722	0.333	1.000	-0.159	0.611	-0.118	0.778	0.100	1.000	0.087	1.000	0.100	0.944
1045240	HLA-A*02:01	10	12	9	t1/2	0.855	1.000	0.914	1.000	0.841	0.889	0.890	1.000	0.823	0.963	0.802	0.889	0.802	0.815	0.795	0.778	0.872	0.963	0.879	0.889	0.785	1.000	0.732	1.000	0.883	1.000	0.858	0.963	0.816	0.963