IEDB Analysis Resource

MHCII Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IED for the last at least 5 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
NN-align 65 65 66
NetMHCIIpan-3.1 78 82 74
Comblib matrices 0 0 0
SMM-align 34 33 36
Tepitope (Sturniolo) 53 44 62
Consensus IEDB method 58 55 61

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


IEDB
Reference
Allele Peptide
Count
Positive
Count
Measurement
type
NN-align NetMHCIIpan-3.1 Comblib matrices SMM-align Tepitope (Sturniolo) Consensus IEDB method
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1031423   0   56   47   ic50   0.040   0.515   0.001   0.501   -   -   0.075   0.565   -   -   0.093   0.606 
 1031406   0   24   16   ic50   0.780   0.992   0.902   0.984   -   -   0.692   0.969   -   -   0.752   0.992 
 1031683   0   17   12   binary   0.738   0.967   0.764   0.983   0.105   0.567   0.580   0.867   0.567   0.858   0.606   0.883 
 1031683   0   16   6   binary   0.196   0.617   0.196   0.617   -   -   0.028   0.517   0.421   0.750   0.056   0.533 
 1031683   0   17   9   binary   0.818   0.972   0.818   0.972   0.253   0.646   0.746   0.931   0.867   1.000   0.770   0.944 
 1031683   0   17   13   binary   0.651   0.942   0.736   1.000   0.144   0.596   0.368   0.750   -   -   0.396   0.769 
 1031683   0   16   11   binary   0.483   0.800   0.307   0.691   -   -   0.570   0.855   0.470   0.818   0.572   0.855 
 1031683   0   17   13   binary   0.340   0.731   0.481   0.827   -   -   0.283   0.692   0.241   0.663   0.425   0.788 
 1031910   0   28   23   binary   -0.462   0.152   -0.462   0.152   -   -   -0.439   0.170   -0.551   0.135   -0.462   0.152 
 1032311   0   16   14   ic50   0.276   0.964   0.432   1.000   0.038   0.589   0.405   1.000   0.268   1.000   0.297   0.964