IEDB Analysis Resource

MHCII Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IED for the last at least 5 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
NN-align 88 91 84
NetMHCIIpan-3.1 55 61 49
Comblib matrices 0 0 0
SMM-align 38 33 44
Tepitope (Sturniolo) 33 27 40
Consensus IEDB method 58 58 59

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


IEDB
Reference
Allele Peptide
Count
Positive
Count
Measurement
type
NN-align NetMHCIIpan-3.1 Comblib matrices SMM-align Tepitope (Sturniolo) Consensus IEDB method
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1034868   0   49   5   ic50   0.528   0.800   0.533   0.818   0.177   0.591   0.315   0.632   0.331   0.673   0.443   0.718 
 1034868   0   49   3   ic50   0.574   0.891   0.566   0.884   -   -   0.478   0.739   0.583   0.808   0.548   0.775 
 1034868   0   49   2   ic50   0.682   0.660   0.588   0.596   0.224   0.500   0.564   0.745   0.537   0.856   0.657   0.734 
 1034868   0   49   4   ic50   0.548   0.950   0.434   0.856   -   -   0.438   0.961   0.224   0.750   0.495   0.989 
 1034868   0   49   10   ic50   0.664   0.918   0.560   0.862   -   -   0.554   0.867   0.524   0.883   0.648   0.917 
 1034384   0   662   75   binary   0.392   0.857   0.370   0.837   0.215   0.699   0.378   0.844   -   -   0.379   0.849 
 1035881   0   10   8   ic50   0.153   0.438   0.006   0.250   -   0.500   0.092   0.250   0.246   0.562   0.157   0.250 
 1035907   0   30   9   binary   0.719   0.952   0.651   0.910   0.391   0.762   0.550   0.847   -   -   0.593   0.873 
 1036372   0   42   2   binary   0.263   0.912   0.291   0.894   -   -   0.254   0.894   0.065   0.769   0.180   0.838