IEDB Analysis Resource

MHCII Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IED for the last at least 2 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
Comblib matrices 37 37 37
Consensus IEDB method 56 56 56
NN-align 66 66 66
NN-align 2.3 56 56 56
NetMHCIIpan-3.1 79 79 79
NetMHCIIpan-3.2 79 79 79
NetMHCIIpan-4.0 BA 64 64 64
NetMHCIIpan-4.0 EL 10 10 11
NetMHCIIpan-4.1 BA 68 68 68
NetMHCIIpan-4.1 EL 10 10 10
NetMHCIIpan-4.2 BA 82 82 82
NetMHCIIpan-4.2 EL 15 15 14
NetMHCIIpan-4.3 BA 82 82 82
NetMHCIIpan-4.3 EL 7 7 7
SMM-align 36 36 36
Tepitope (Sturniolo) 48 48 48

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


IEDB
Reference		 Allele Peptide
Count		 Positive
Count		 Measurement
type		 Comblib matrices Consensus IEDB method NN-align NN-align 2.3 NetMHCIIpan-3.1 NetMHCIIpan-3.2 NetMHCIIpan-4.0 BA NetMHCIIpan-4.0 EL NetMHCIIpan-4.1 BA NetMHCIIpan-4.1 EL NetMHCIIpan-4.2 BA NetMHCIIpan-4.2 EL NetMHCIIpan-4.3 BA NetMHCIIpan-4.3 EL SMM-align Tepitope (Sturniolo)
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1043121   HLA-DRB1*01:01   89   28   binary   0.627   0.890   0.621   0.888   0.642   0.899   0.637   0.896   0.666   0.914   0.665   0.913   0.653   0.906   0.302   0.695   0.656   0.908   0.319   0.708   0.663   0.912   0.302   0.694   0.648   0.903   0.291   0.684   0.572   0.858   0.448   0.792 
 1043121   HLA-DRB1*03:01   89   6   binary   -   -   0.369   0.939   0.389   0.948   0.363   0.918   0.419   0.982   0.412   0.974   0.385   0.944   0.229   0.765   0.392   0.952   0.244   0.781   0.391   0.950   0.238   0.774   0.410   0.972   0.255   0.791   0.346   0.898   0.281   0.840 
 1043121   HLA-DRB1*04:01   89   27   binary   -   -   0.598   0.879   0.553   0.847   0.544   0.842   0.545   0.842   0.531   0.833   0.511   0.821   0.280   0.688   0.499   0.813   0.260   0.668   0.534   0.835   0.299   0.693   0.550   0.845   0.278   0.678   0.518   0.826   0.619   0.892 
 1043121   HLA-DRB1*07:01   89   26   binary   0.550   0.849   0.678   0.935   0.617   0.892   0.692   0.939   0.706   0.948   0.700   0.944   0.712   0.952   0.438   0.785   0.713   0.952   0.388   0.748   0.725   0.960   0.426   0.773   0.728   0.962   0.398   0.755   0.622   0.895   0.642   0.918 
 1043570   HLA-DRB1*15:01   146   13   binary   -   -   0.357   0.867   0.377   0.882   0.370   0.875   0.366   0.871   0.378   0.883   0.375   0.880   0.249   0.763   0.374   0.879   0.263   0.770   0.379   0.884   0.267   0.780   0.375   0.880   0.244   0.758   0.314   0.818   0.322   0.848