If you want to run the MHC class I and class II binding prediction tools as stand-alone tools on your local machine, please follow the links provided below.
You will need Linux operating system to use this package.
The tool package is available to academia and non-profit for free while a license fee applies to industry. Please email us at license@iedb.org to get information on license.

MHC class I prediction tool and data sets

MHC class II prediction tool and data sets