IEDB Analysis Resource

MHC-II binding dataset - Download

This MHC class II binding affinity dataset consists of 44, 541 experimentally measured binging affinities covering 26 alleric variants.

Two sets of randomly splitted 5-fold cross validation data are provided: the entire dataset ("ALL") and the similarity reduced dataset ("SR").

To download the dataset in tar.gz format:

Prediction scores for MHC-II binding dataset - Download

The prediction scores for the six implemented algorithms based on above dataset can be download here. The scores were generate via 5-fold cross validation based on two sets of data: the entire dataset ("ALL") and the similarity reduced dataset "SR".

To download the scores in tar.gz format:

Combinatorial peptide scanning library scoring matrices - Download

This file contains the scoring matrices for sixteen MHC class II alleles developed from the combinatorial peptide scanning library data.

To download the dataset in tar.gz format:

MHC-II binding predictions - Download

The MHC_II binding tool contains a collection of following peptide binding prediction methods

for Major Histocompatibility Complex (MHC) class II molecules.The collection is a mixture of pythons scripts and linux 32-bit environment specific binaries.

License Agreements

By downloading the MHC_II binding tool, you are consenting to be bound by and become a party as the "Licensee" for the use of NetMHC 3.0".

Also you are consenting the terms and conditions of the Non-Profit Open Software License ("Non-Profit OSL") version 3.0

Please read folowing two agreements before proceeding. If you do not agree to all of the terms of these two agreements, you must not click the download button, not install the product nor use the product, and you do not become a LICENSEE under these agreements.

To download the tools in tar.gz format:

To download the tools as a Debian package:

To install to a machine running Ubuntu Linux 8.04 or later via the package management system, please follow these steps:

  • Add the following line to your '/etc/apt/sources.list' file:

    deb hardy contrib
  • Open the terminal and issue the following command:

    $ sudo apt-get update && sudo apt-get install iedbtools-mhc-ii

To return to the main page: