IEDB Analysis Resource
T Cell Tools
B Cell Tools
B Cell Epitope Prediction Tools
The tools here are intended to predict regions of proteins that are likely to be recognized as epitopes in the context of a B cell response.
Prediction of linear epitopes from protein sequence
A collection of methods to predict linear B cell epitopes based on sequence characteristics of the antigen using amino acid scales and HMMs.
Discotope - Prediction of epitopes from protein structure
This method incorporates solvent-accessible surface area calculations, as well as contact distances into its prediction of B cell epitope potential along the length of a protein sequence.
ElliPro - Epitope prediction based upon structural protrusion
This method predicts epitopes based upon solvent-accessibility and flexibility.
Paratome - prediction of Antigen binding regions
This method, developed by the
lab of Yanay Ofran
, can be used to predict the antigen binding regions (ABRs) of antibodies and accepts either a sequence or PDB structure as input.
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